MuScle-logoMuScle - Molecule ID B0532

geneAKT3, PKBG
nameRAC-gamma serine/threonine protein kinase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AKT3_HUMANQ9Y243ENSG0000011702010000Hs.498292603387, 611223

Functions and classifications

GOC:Golgi apparatus, C:nucleus, C:plasma membrane, F:ATP binding, F:protein serine/threonine kinase activity, P:mitochondrial genome maintenance, P:signal transduction, F:phospholipid binding
UniProt3D-structure, Acetylation, Alternative splicing, ATP-binding, Complete proteome, Cytoplasm, Disease mutation, Disulfide bond, Glycoprotein, Kinase, Membrane, Nucleotide-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Serine/threonine-protein kinase, Transferase, Ubl conjugation
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)0.580.010548220921521
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)3.010.005220620921521
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_12_month_follow-up) (Multiple sclerosis)0.820.0287854121886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.552.05E-0221886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.152.66E-0222021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.810.04528622252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.340.007280522252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.202.89E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.282.22E-0522252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.981.28E-0722252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)2.410.0025781922491253
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.191.05E-0223895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.241.32E-0323895517

Compile date 09-07-2016© MuScle project