MuScle-logoMuScle - Molecule ID B0529

geneAKAP13, BRX, HT31
nameA-kinase anchoring protein 13
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AKP13_HUMANQ12802ENSG0000017077611214Hs.459211604686

Functions and classifications

GOC:cytosol, C:membrane, C:nucleus, C:perinuclear region of cytoplasm, F:cAMP-dependent protein kinase activity, F:metal ion binding, F:Rho guanyl-nucleotide exchange factor activity, F:signal transducer activity, P:apoptotic signaling pathway, P:neurotrophin TRK receptor signaling pathway, P:nuclear export, P:positive regulation of apoptotic process, P:regulation of cardiac muscle hypertrophy, P:regulation of glucocorticoid mediated signaling pathway, P:regulation of protein kinase activity, P:regulation of Rho GTPase activity, P:small GTPase mediated signal transduction, F:kinase activity, C:cytoplasm, P:intracellular signal transduction, F:phospholipid binding, P:apoptotic process, P:nerve growth factor receptor signaling pathway, P:regulation of Rho protein signal transduction, P:regulation of small GTPase mediated signal transduction, C:intracellular
UniProt3D-structure, Alternative splicing, Coiled coil, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Membrane, Metal-binding, Nucleus, Phosphoprotein, Polymorphism, Proto-oncogene, Reference proteome, Zinc, Zinc-finger, Kinase, Transferase
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.782.73E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)1.120.0401969920136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.880.039225620136355
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)3.180.026010521216829
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.290.0391598421216829
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.603.72E-0522021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.611.46E-0722021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.687.15E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.691.25E-0722021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.791.50E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.834.60E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.151.07E-0222021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)1.443.53E-0222252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.580.026948822252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.780.038803822252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.637.50E-0322252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.652.15E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.761.14E-0222252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.172.29E-0523895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.181.61E-0323895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.242.45E-0323895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.242.89E-0323895517

Compile date 09-07-2016© MuScle project