MuScle-logoMuScle - Molecule ID B0526

geneAKIRIN2
nameAkirin-2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AKIR2_HUMANQ53H80ENSG0000013533455122Hs.485915615165

Functions and classifications

GOC:transcriptional repressor complex, P:embryo development, P:innate immune response, P:negative regulation of transcription from RNA polymerase II promoter, P:positive regulation of cell proliferation, P:positive regulation of endopeptidase activity, P:positive regulation of interleukin-6 production, P:positive regulation of transcription from RNA polymerase II promoter, P:response to lipopolysaccharide, P:transcription, DNA-templated, C:transcriptional repressor complex, P:negative regulation of transcription, DNA-dependent, P:transcription, DNA-dependent", P:response to lipopolysaccharide"
UniProtComplete proteome, Developmental protein, Immunity, Innate immunity, Nucleus, Phosphoprotein, Reference proteome, Repressor, Transcription, Transcription regulation
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.770.0479090720136355
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.120.0154074921216829
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.431.60E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_3_month_follow-up) (Multiple sclerosis)1.450.045112321886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.447.12E-0522021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.798.54E-0422021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.875.24E-0722021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.281.09E-0722252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.316.20E-0822252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.322.57E-1122252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)0.620.0407393122491253
Exp24850724Homo sapiens12Blood CIS (Multiple sclerosis)0.610.0105818124850724

Compile date 09-07-2016© MuScle project