MuScle-logoMuScle - Molecule ID B0510

geneAKAP1, AKAP149, PRKA1
nameA kinase anchor protein 1, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AKAP1_HUMANQ92667ENSG000001210578165Hs.463506602449

Functions and classifications

GOC:cytosol, C:integral component of membrane, C:mitochondrial outer membrane, C:mitochondrion, F:RNA binding, P:blood coagulation, F:kinase activity, C:integral to membrane, C:lipid particle, C:mitochondrial crista, C:mitochondrial matrix, C:neuromuscular junction, C:postsynaptic membrane, P:cellular response to insulin stimulus, P:negative regulation of cardiac muscle hypertrophy, P:negative regulation of NFAT protein import into nucleus, P:negative regulation of protein dephosphorylation
UniProtAlternative splicing, Complete proteome, Membrane, Mitochondrion, Mitochondrion outer membrane, Phosphoprotein, Polymorphism, Reference proteome, RNA-binding, Transit peptide, Transmembrane, Kinase, Transferase
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)0.753.12E-0217467740
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)0.784.82E-0217467740
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.820.0011653820136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_12_month_follow-up) (Multiple sclerosis)0.760.0346151621886806
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.922.52E-0622252466

Compile date 09-07-2016© MuScle project