MuScle-logoMuScle - Molecule ID B0508

geneAKAP12, AKAP250
nameA-kinase anchor protein 12
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AKA12_HUMANQ02952ENSG000001310169590Hs.371240604698

Functions and classifications

GOC:cell cortex, C:cytoplasm, C:cytoskeleton, C:plasma membrane, F:protein kinase A binding, P:G-protein coupled receptor signaling pathway, P:positive regulation of cAMP biosynthetic process, P:positive regulation of protein kinase A signaling, P:protein targeting, P:regulation of protein kinase C signaling, P:signal transduction, P:positive regulation of protein kinase A signaling cascade
UniProtAlternative splicing, Complete proteome, Cytoplasm, Cytoskeleton, Lipoprotein, Myristate, Phosphoprotein, Polymorphism, Reference proteome, Repeat
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.651.21E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.711.54E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.810.0412010120136355
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.110.0309355521216829
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.200.0366706921216829
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.376.86E-0622021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.778.84E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.908.35E-0322021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.873.33E-0322252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)2.040.0430604922491253

Compile date 09-07-2016© MuScle project