MuScle-logoMuScle - Molecule ID B0494

geneAIRE, APECED
nameAutoimmune regulator
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AIRE_HUMANO43918ENSG00000160224326Hs.129829109100, 240300, 607358

Functions and classifications

GOC:actin cytoskeleton, C:cytoplasm, C:nucleus, C:plasma membrane, F:chromatin binding, F:histone binding, F:transcription regulatory region DNA binding, F:translation regulator activity, F:zinc ion binding, P:humoral immune response, P:immune response, P:positive regulation of transcription from RNA polymerase II promoter, P:positive regulation of transcription, DNA-templated, P:regulation of translation, P:transcription, DNA-templated, F:metal ion binding, P:positive regulation of transcription, DNA-dependent, P:transcription, DNA-dependent"
UniProt3D-structure, Activator, Alternative splicing, Complete proteome, Cytoplasm, Direct protein sequencing, Disease mutation, DNA-binding, Metal-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transcription, Transcription regulation, Zinc, Zinc-finger
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.862.04E-0222252466

Compile date 09-07-2016© MuScle project