MuScle-logoMuScle - Molecule ID B0489

geneAIMP1, EMAP2, SCYE1
nameMultisynthetase complex auxiliary component p43
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AIMP1_HUMANQ12904ENSG000001640229255Hs.591680260600, 603605

Functions and classifications

GOC:aminoacyl-tRNA synthetase multienzyme complex, C:cell surface, C:cytosol, C:endoplasmic reticulum, C:extracellular space, C:Golgi apparatus, C:nucleus, C:transport vesicle, F:cytokine activity, F:protein homodimerization activity, F:tRNA binding, P:angiogenesis, P:apoptotic process, P:cell adhesion, P:cell-cell signaling, P:chemotaxis, P:glucose metabolic process, P:inflammatory response, P:leukocyte migration, P:negative regulation of endothelial cell proliferation, P:signal transduction, P:tRNA aminoacylation for protein translation, F:cell surface binding
UniProt3D-structure, Acetylation, Alternative splicing, Angiogenesis, Apoptosis, Carbohydrate metabolism, Cell adhesion, Complete proteome, Cytokine, Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Glucose metabolism, Golgi apparatus, Inflammatory response, Leukodystrophy, Nucleus, Polymorphism, Protein biosynthesis, Reference proteome, RNA-binding, Secreted, tRNA-binding
PADBMOD: modulator, regulator

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)1.125.48E-0320136355
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.731.12E-0322021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.300.009541422252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.371.42E-0222252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)1.580.0350866222491253
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.625.15E-0623895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.711.12E-0423895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.851.08E-0223895517

Compile date 09-07-2016© MuScle project