MuScle-logoMuScle - Molecule ID B0484

geneAIFM3, AIFL
nameApoptosis-inducing factor 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
AIFM3_HUMANQ96NN9ENSG00000183773150209Hs.723246

Functions and classifications

GOC:endoplasmic reticulum, C:mitochondrial inner membrane, F:2 iron, 2 sulfur cluster binding, F:flavin adenine dinucleotide binding, F:metal ion binding, F:oxidoreductase activity, P:cell redox homeostasis, P:execution phase of apoptosis, "C:mitochondrion, P:cell redox homeostasis", F:oxidoreductase activity", "F:2 iron, 2 sulfur cluster binding, F:cysteine-type endopeptidase activator activity involved in apoptotic process, P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, P:electron transport chain, P:induction of apoptosis, P:mitochondrial depolarization", "C:cytoplasm
UniProt2Fe-2S, Alternative splicing, Apoptosis, Complete proteome, Electron transport, FAD, Flavoprotein, Iron, Iron-sulfur, Metal-binding, Mitochondrion, Oxidoreductase, Polymorphism, Reference proteome, Transport
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.385.60E-0822252466

Compile date 09-07-2016© MuScle project