MuScle-logoMuScle - Molecule ID B0483

geneAIFM2, AMID, PRG3
nameP53-responsive gene 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AIFM2_HUMANQ9BRQ8ENSG0000004228684883Hs.650680605159

Functions and classifications

GOC:cytosol, C:integral component of membrane, C:lipid particle, C:mitochondrial outer membrane, F:DNA binding, F:electron-transferring-flavoprotein dehydrogenase activity, F:flavin adenine dinucleotide binding, P:apoptotic mitochondrial changes, P:chromosome condensation, P:execution phase of apoptosis, C:integral to membrane, P:induction of apoptosis
UniProtAlternative splicing, Apoptosis, Complete proteome, Cytoplasm, DNA-binding, FAD, Flavoprotein, Lipoprotein, Membrane, Mitochondrion, Mitochondrion outer membrane, Myristate, Oxidoreductase, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.260.049504720136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_3_month_follow-up) (Multiple sclerosis)1.270.034692821886806
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.692.95E-0522252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.741.02E-0222252466

Compile date 09-07-2016© MuScle project