MuScle-logoMuScle - Molecule ID B0480

geneAIF1, G1, IBA1
nameAllograft inflammatory factor-1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AIF1_HUMANP55008ENSG00000204472|ENSG00000206428|ENSG00000235985|ENSG00000237727|ENSG00000234836|ENSG00000235588199Hs.76364601833

Functions and classifications

GOC:actin filament, C:cytosol, C:lamellipodium, C:nucleus, C:perinuclear region of cytoplasm, C:phagocytic cup, C:ruffle membrane, F:actin filament binding, F:calcium ion binding, P:actin filament bundle assembly, P:actin filament polymerization, P:cellular response to interferon-gamma, P:inflammatory response, P:microglial cell activation, P:negative regulation of smooth muscle cell chemotaxis, P:negative regulation of smooth muscle cell proliferation, P:phagocytosis, engulfment, P:positive regulation of G1/S transition of mitotic cell cycle, P:positive regulation of monocyte chemotaxis, P:positive regulation of smooth muscle cell chemotaxis, P:positive regulation of smooth muscle cell proliferation, P:positive regulation of T cell migration, P:positive regulation of T cell proliferation, P:Rac protein signal transduction, P:ruffle assembly, C:cytoplasm, P:ruffle assembly, C:perikaryon, P:cellular response to extracellular stimulus, P:cellular response to hormone stimulus, P:negative regulation of apoptotic process, P:negative regulation of gene expression, P:positive regulation of muscle hyperplasia, P:positive regulation of nitric oxide biosynthetic process, P:positive regulation of protein phosphorylation, P:response to axon injury, P:response to electrical stimulus, C:ruffle, P:positive regulation of cell migration, P:response to cytokine stimulus
UniProt3D-structure, Acetylation, Actin-binding, Alternative splicing, Calcium, Cell membrane, Cell projection, Complete proteome, Cytoplasm, Cytoskeleton, Membrane, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.943.63E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.261.24E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.297.55E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.333.72E-0322021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.289.33E-1322252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.722.90E-0323895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.751.65E-0323895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.754.42E-0423895517

Compile date 09-07-2016© MuScle project