MuScle-logoMuScle - Molecule ID B0473

geneAHR, BHLHE76
nameAryl hydrocarbon receptor precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AHR_HUMANP35869ENSG00000106546196Hs.171189600253

Functions and classifications

GOC:cytosolic aryl hydrocarbon receptor complex, C:nucleus, C:transcription factor complex, F:Hsp90 protein binding, F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, F:protein heterodimerization activity, F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, F:sequence-specific DNA binding, F:signal transducer activity, F:transcription regulatory region DNA binding, P:apoptotic process, P:blood vessel development, P:cell cycle, P:negative regulation of transcription from RNA polymerase II promoter, P:positive regulation of RNA polymerase II transcriptional preinitiation complex assembly, P:prostate gland development, P:regulation of B cell proliferation, P:response to stress, P:xenobiotic metabolic process, P:cellular response to glucocorticoid stimulus, P:ovarian follicle development, P:response to estradiol stimulus
UniProtAcetylation, Activator, Cell cycle, Complete proteome, Cytoplasm, DNA-binding, Nucleus, Polymorphism, Receptor, Reference proteome, Repeat, Transcription, Transcription regulation
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.370.0133742720136355
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.304.01E-0322021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.295.70E-0722252466

Compile date 09-07-2016© MuScle project