MuScle-logoMuScle - Molecule ID B0456

geneAGK, MULK
nameAcylglycerol kinase, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AGK_HUMANQ53H12ENSG00000006530|ENSG0000026232755750Hs.743318212350, 610345, 614691

Functions and classifications

GOC:mitochondrial membrane, F:acylglycerol kinase activity, F:ATP binding, F:ceramide kinase activity, F:diacylglycerol kinase activity, F:NAD+ kinase activity, P:ceramide biosynthetic process, P:glycerolipid metabolic process, P:protein kinase C-activating G-protein coupled receptor signaling pathway, P:phosphorylation, C:membrane, C:mitochondrion
UniProtAlternative splicing, ATP-binding, Cardiomyopathy, Cataract, Complete proteome, Kinase, Membrane, Mitochondrion, Nucleotide-binding, Polymorphism, Reference proteome, Transferase, Transit peptide, Acetylation
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)1.193.27E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.841.94E-0320136355
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)0.300.022510521216829
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.114.53E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.366.15E-0622252466

Compile date 09-07-2016© MuScle project