MuScle-logoMuScle - Molecule ID B0445

nameARF-GAP with GTPase, ANK repeat and PH domain-containing protein 2
speciesHomo sapiens

Molecule reference


Functions and classifications

GOC:mitochondrion, C:nucleolus, F:ARF GTPase activator activity, F:GTP binding, F:zinc ion binding, P:axon guidance, P:negative regulation of neuron apoptotic process, P:negative regulation of protein catabolic process, P:positive regulation of GTPase activity, P:protein transport, P:regulation of ARF GTPase activity, P:small GTPase mediated signal transduction, C:nucleus, F:protein kinase activator activity, P:mammary gland alveolus development, P:negative regulation of apoptotic process, P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, P:positive regulation of JAK-STAT cascade, P:positive regulation of mammary gland epithelial cell proliferation, P:positive regulation of transcription from RNA polymerase II promoter, C:intracellular, F:metal ion binding, F:phospholipid binding, C:cytosol, P:positive regulation of protein kinase activity
UniProt3D-structure, Alternative splicing, ANK repeat, Complete proteome, Cytoplasm, GTP-binding, GTPase activation, Metal-binding, Nucleotide-binding, Nucleus, Phosphoprotein, Polymorphism, Protein transport, Reference proteome, Repeat, Transport, Tumor suppressor, Zinc, Zinc-finger
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)4.440.034999321216829
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.370.0423145121216829
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)3.563.91E-1022252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.063.35E-0223895517

Compile date 09-07-2016© MuScle project