MuScle-logoMuScle - Molecule ID B0438

geneAFG3L2
nameAFG3-like protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AFG32_HUMANQ9Y4W6ENSG0000014138510939Hs.726355604581, 610246, 614487

Functions and classifications

GOC:integral component of membrane, C:mitochondrial inner membrane, C:mitochondrion, F:ATP binding, F:metalloendopeptidase activity, F:nucleoside-triphosphatase activity, F:unfolded protein binding, F:zinc ion binding, P:axonogenesis, P:cell death, P:cristae formation, P:mitochondrial fusion, P:mitochondrial protein processing, P:muscle fiber development, P:myelination, P:nerve development, P:neuromuscular junction development, P:proteolysis, P:regulation of multicellular organism growth, P:righting reflex, P:death, C:integral to membrane, F:metal ion binding, P:protein catabolic process
UniProt3D-structure, ATP-binding, Complete proteome, Disease mutation, Hydrolase, Membrane, Metal-binding, Metalloprotease, Mitochondrion, Neurodegeneration, Nucleotide-binding, Protease, Reference proteome, Spinocerebellar ataxia, Transmembrane, Transmembrane helix, Zinc, Acetylation
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.743.94E-0221886806
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.627.90E-0322252466
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.734.06E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.045.65E-0622252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.251.96E-0522252466

Compile date 09-07-2016© MuScle project