MuScle-logoMuScle - Molecule ID B0437

geneAFF3, LAF4
nameAF4/FMR2 family member 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AFF3_HUMANP51826ENSG000001442183899Hs.444414601464

Functions and classifications

GOC:nucleolus, F:double-stranded DNA binding, P:embryonic hindlimb morphogenesis, P:regulation of transcription, DNA-templated, P:response to tumor necrosis factor, P:transcription, DNA-templated, P:regulation of transcription, DNA-dependent, P:transcription, DNA-dependent"
UniProtActivator, Alternative splicing, Complete proteome, DNA-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Transcription, Transcription regulation
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.662.07E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.745.56E-0320136355
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.230.0281440921216829
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.520.0326126521216829
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.563.98E-0221886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.372.68E-0522021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.647.46E-0522021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.845.21E-0322021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.211.69E-0222252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)2.360.0091129222491253

Compile date 09-07-2016© MuScle project