MuScle-logoMuScle - Molecule ID B0436

geneAFF2, FMR2, OX19
nameFragile X mental retardation 2 protein
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AFF2_HUMANP51816ENSG00000155966|ENSG000002697542334Hs.496911300806, 309548

Functions and classifications

GOC:nuclear speck, F:G-quadruplex RNA binding, P:brain development, P:learning or memory, P:mRNA processing, P:regulation of RNA splicing, P:RNA splicing
UniProtAlternative splicing, Complete proteome, Mental retardation, mRNA processing, mRNA splicing, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, RNA-binding, Triplet repeat expansion
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.771.60E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.730.0097680420136355
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)32.000.027157121216829
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_12_month_follow-up) (Multiple sclerosis)1.190.032740421886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.204.89E-0221886806
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.170.006791522252466

Compile date 09-07-2016© MuScle project