MuScle-logoMuScle - Molecule ID B0435

geneAFF1, AF-4, MLLT2
nameAF4/FMR2 family member 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AFF1_HUMANP51825ENSG000001724934299Hs.480190159557

Functions and classifications

GOC:nucleus, F:sequence-specific DNA binding transcription factor activity, P:positive regulation of transcription, DNA-templated, C:nucleus, P:positive regulation of transcription, DNA-dependent"
UniProt3D-structure, Acetylation, Alternative splicing, Chromosomal rearrangement, Complete proteome, Nucleus, Phosphoprotein, Polymorphism, Proto-oncogene, Reference proteome
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)1.593.94E-0217467740
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.190.024891821886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_3_month_follow-up) (Multiple sclerosis)1.240.006678121886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.151.52E-0222021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)1.301.21E-0222252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.810.047321722252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.084.25E-0522252466

Compile date 09-07-2016© MuScle project