MuScle-logoMuScle - Molecule ID B0430

geneAFAP1L2, XB130
nameActin filament-associated protein 1-like 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AF1L2_HUMANQ8N4X5ENSG0000016912984632Hs.501106612420

Functions and classifications

GOC:aggresome, C:cytoplasm, C:nucleus, C:plasma membrane, F:protein tyrosine kinase activator activity, P:inflammatory response, P:positive regulation of epidermal growth factor receptor signaling pathway, P:positive regulation of interleukin-8 production, P:positive regulation of transcription, DNA-templated, P:regulation of interleukin-6 production, P:regulation of mitotic cell cycle, C:aggresome, F:phospholipid binding, P:positive regulation of transcription, DNA-dependent
UniProt3D-structure, Alternative splicing, Coiled coil, Complete proteome, Cytoplasm, Phosphoprotein, Polymorphism, Reference proteome, Repeat
PADBUK: unknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.172.54E-1122252466
Exp24850724Homo sapiens12Blood CIS (Multiple sclerosis)2.080.0217547624850724

Compile date 09-07-2016© MuScle project