MuScle-logoMuScle - Molecule ID B0428

geneAF10, MLLT10, MLL/AF10 fusion
nameAF-10 protein
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AF10_HUMANP55197ENSG000000784038028Hs.30385602409

Functions and classifications

GOC:cytoplasm, C:nucleus, F:DNA binding, F:sequence-specific DNA binding transcription factor activity, F:zinc ion binding, P:positive regulation of transcription from RNA polymerase II promoter, P:transcription, DNA-templated, C:cytoplasm, F:metal ion binding, P:transcription, DNA-dependent"
UniProtAlternative splicing, Chromosomal rearrangement, Complete proteome, DNA-binding, Metal-binding, Nucleus, Phosphoprotein, Proto-oncogene, Reference proteome, Repeat, Transcription, Transcription regulation, Zinc, Zinc-finger
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_6_month_follow-up) (Multiple sclerosis)1.322.68E-0217467740
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.680.0224068220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.710.0067087420136355
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)2.220.005596920921521
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.394.53E-0722021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.737.64E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.783.12E-0522021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.871.32E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.221.40E-0322021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.461.46E-0322252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.491.72E-0422252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.777.73E-0722252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.902.23E-0522252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.104.34E-0522252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)4.740.0312733922491253
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.762.46E-0323895517

Compile date 09-07-2016© MuScle project