MuScle-logoMuScle - Molecule ID B0403

geneADNP, ADNP1
nameActivity-dependent neuroprotector
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADNP_HUMANQ9H2P0ENSG0000010112623394Hs.570355611386

Functions and classifications

GOC:extracellular space, C:nucleus, F:chromatin binding, F:metal ion binding, F:sequence-specific DNA binding, F:sequence-specific DNA binding transcription factor activity, P:negative regulation of neuron apoptotic process, P:transcription, DNA-templated, C:extracellular space, "C:axon, C:cytoplasm, C:dendrite, C:neuronal cell body, F:copper ion binding, F:peptide binding, F:zinc ion binding, P:activation of protein kinase activity, P:cellular response to extracellular stimulus, P:estrous cycle phase, P:negative regulation of gene expression, P:negative regulation of protein binding, P:negative regulation of synaptic transmission, P:nitric oxide homeostasis, P:positive regulation of axon extension, P:positive regulation of cGMP biosynthetic process, P:positive regulation of neuron projection development, P:positive regulation of peptidyl-tyrosine phosphorylation, P:positive regulation of synapse assembly, P:regulation of protein ADP-ribosylation, P:response to carbohydrate stimulus, P:response to inorganic substance, P:short-term memory, P:transcription, DNA-dependent", C:axon
UniProtAcetylation, Complete proteome, DNA-binding, Homeobox, Metal-binding, Nucleus, Phosphoprotein, Reference proteome, Repeat, Transcription, Transcription regulation, Zinc, Zinc-finger
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.890.0292960520136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.770.018296121886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.164.35E-0522021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.442.48E-0722021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.390.022839522252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.819.45E-0822252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.967.40E-0922252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.229.10E-0423895517

Compile date 09-07-2016© MuScle project