MuScle-logoMuScle - Molecule ID B0402

geneADM, AM
nameADM precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADML_HUMANP35318ENSG00000148926133Hs.441047103275

Functions and classifications

GOC:cytoplasm, C:extracellular space, F:receptor binding, P:aging, P:androgen metabolic process, P:blood circulation, P:branching involved in labyrinthine layer morphogenesis, P:cAMP biosynthetic process, P:cAMP-mediated signaling, P:cell-cell signaling, P:developmental growth, P:female pregnancy, P:G-protein coupled receptor internalization, P:heart development, P:hormone secretion, P:negative regulation of cell proliferation, P:negative regulation of vascular permeability, P:negative regulation of vasoconstriction, P:neural tube closure, P:neuron projection regeneration, P:odontogenesis of dentin-containing tooth, P:organ regeneration, P:positive regulation of angiogenesis, P:positive regulation of apoptotic process, P:positive regulation of cAMP biosynthetic process, P:positive regulation of cell proliferation, P:positive regulation of cytosolic calcium ion concentration, P:positive regulation of heart rate, P:positive regulation of vasculogenesis, P:positive regulation of vasodilation, P:progesterone biosynthetic process, P:regulation of the force of heart contraction, P:response to cold, P:response to glucocorticoid, P:response to hypoxia, P:response to insulin, P:response to lipopolysaccharide, P:response to starvation, P:response to wounding, P:signal transduction, P:spongiotrophoblast layer development, P:vascular smooth muscle cell development, P:vasculogenesis, C:extracellular region, P:elevation of cytosolic calcium ion concentration, P:response to glucocorticoid stimulus, P:response to insulin stimulus
UniProt3D-structure, Amidation, Cleavage on pair of basic residues, Complete proteome, Direct protein sequencing, Disulfide bond, Hormone, Polymorphism, Reference proteome, Secreted, Signal
PADBSIG: signalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.360.0025662320136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.310.0284423920136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_12_month_follow-up) (Multiple sclerosis)2.070.0234149821886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)2.588.04E-0321886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.724.30E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.022.25E-0922252466

Compile date 09-07-2016© MuScle project