MuScle-logoMuScle - Molecule ID B0399

geneADK
nameAdenosine kinase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADK_HUMANP55263ENSG00000156110132Hs.656586102750, 614300

Functions and classifications

GOC:cytosol, C:nucleus, F:adenosine kinase activity, F:ATP binding, F:metal ion binding, F:phosphotransferase activity, alcohol group as acceptor, P:adenosine metabolic process, P:AMP salvage, P:circadian regulation of gene expression, P:dATP biosynthetic process, P:positive regulation of cardiac muscle hypertrophy, P:positive regulation of T cell proliferation, P:purine nucleobase metabolic process, P:purine ribonucleoside salvage, P:purine-containing compound salvage, P:type B pancreatic cell proliferation, "F:adenosine kinase activity, P:AMP biosynthetic process, P:purine ribonucleoside salvage", C:cytosol, P:type B pancreatic cell proliferation, P:purine-containing compound salvage"
UniProt3D-structure, Acetylation, Alternative splicing, ATP-binding, Complete proteome, Cytoplasm, Direct protein sequencing, Disease mutation, Kinase, Magnesium, Metal-binding, Nucleotide-binding, Nucleus, Phosphoprotein, Purine salvage, Reference proteome, Transferase
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)0.644.16E-0217467740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.596.09E-0622021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.662.55E-0522021740
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.883.88E-0223895517

Compile date 09-07-2016© MuScle project