MuScle-logoMuScle - Molecule ID B0381

geneADCY9
nameAdenylate cyclase type 9
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADCY9_HUMANO60503ENSG00000162104115Hs.391860603302

Functions and classifications

GOC:axon, C:dendrite, C:integral component of plasma membrane, F:adenylate cyclase activity, F:ATP binding, F:metal ion binding, P:activation of phospholipase C activity, P:activation of protein kinase A activity, P:adenylate cyclase-activating G-protein coupled receptor signaling pathway, P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, P:cellular response to glucagon stimulus, P:energy reserve metabolic process, P:epidermal growth factor receptor signaling pathway, P:fibroblast growth factor receptor signaling pathway, P:innate immune response, P:intracellular signal transduction, P:neurotrophin TRK receptor signaling pathway, P:synaptic transmission, P:transmembrane transport, P:water transport, C:integral component of membrane, F:nucleotide binding, F:phosphorus-oxygen lyase activity, P:cyclic nucleotide biosynthetic process, C:integral to plasma membrane, C:intracellular, P:nerve growth factor receptor signaling pathway
UniProtATP-binding, cAMP biosynthesis, Complete proteome, Glycoprotein, Lyase, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.726.21E-0321886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.780.03281221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.720.006485621886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_3_month_follow-up) (Multiple sclerosis)0.780.0352567121886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.626.99E-0522021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)1.254.10E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.455.05E-0822252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.697.20E-0522252466

Compile date 09-07-2016© MuScle project