MuScle-logoMuScle - Molecule ID B0380

geneADCY8
nameAdenylate cyclase, type VIII
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADCY8_HUMANP40145ENSG00000155897114Hs.591859103070

Functions and classifications

GOC:integral component of membrane, C:plasma membrane, F:ATP binding, F:calcium- and calmodulin-responsive adenylate cyclase activity, F:metal ion binding, P:activation of phospholipase C activity, P:activation of protein kinase A activity, P:adenylate cyclase-activating G-protein coupled receptor signaling pathway, P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, P:cellular response to glucagon stimulus, P:energy reserve metabolic process, P:epidermal growth factor receptor signaling pathway, P:fibroblast growth factor receptor signaling pathway, P:innate immune response, P:intracellular signal transduction, P:learning or memory, P:long-term memory, P:neurotrophin TRK receptor signaling pathway, P:synaptic transmission, P:transmembrane transport, P:water transport, F:adenylate cyclase activity, F:nucleotide binding, P:cAMP biosynthetic process, C:integral to membrane, C:intracellular, P:cAMP-mediated signaling, P:nerve growth factor receptor signaling pathway
UniProtATP-binding, cAMP biosynthesis, Complete proteome, Glycoprotein, Lyase, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10BloodRRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)1.324.38E-0217467740
Exp20136355Homo sapiens50BloodRRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)0.670.0062432920136355

Compile date 09-07-2016© MuScle project