MuScle-logoMuScle - Molecule ID B0378

geneADCY6
nameAdenylate cyclase type 6
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADCY6_HUMANO43306ENSG00000174233112Hs.525401600294

Functions and classifications

GOC:cilium, C:integral component of membrane, C:plasma membrane, F:adenylate cyclase activity, F:ATP binding, F:metal ion binding, F:protein kinase binding, P:activation of phospholipase C activity, P:activation of protein kinase A activity, P:adenylate cyclase-activating G-protein coupled receptor signaling pathway, P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, P:cellular response to catecholamine stimulus, P:cellular response to glucagon stimulus, P:cellular response to prostaglandin E stimulus, P:dopamine receptor signaling pathway, P:energy reserve metabolic process, P:epidermal growth factor receptor signaling pathway, P:fibroblast growth factor receptor signaling pathway, P:innate immune response, P:intracellular signal transduction, P:neurotrophin TRK receptor signaling pathway, P:synaptic transmission, P:transmembrane transport, P:water transport, P:cAMP biosynthetic process, F:phosphorus-oxygen lyase activity, P:cyclic nucleotide biosynthetic process, C:endosome, C:integral to membrane, C:membrane raft, C:microvillus membrane, C:sarcolemma, F:calcium- and calmodulin-responsive adenylate cyclase activity, P:nerve growth factor receptor signaling pathway, C:intracellular
UniProtAlternative splicing, ATP-binding, cAMP biosynthesis, Cell projection, Cilium, Complete proteome, Glycoprotein, Lyase, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)10.635.52E-1622252466
Exp24850724Homo sapiens12Blood CIS (Multiple sclerosis)2.610.0201828224850724

Compile date 09-07-2016© MuScle project