MuScle-logoMuScle - Molecule ID B0377

geneADCY5
nameAdenylate cyclase 5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADCY5_HUMANO95622ENSG00000173175111Hs.593292600293, 606703

Functions and classifications

GOC:integral component of membrane, C:plasma membrane, C:primary cilium, F:adenylate cyclase activity, F:adenylate cyclase binding, F:ATP binding, F:metal ion binding, F:protein heterodimerization activity, P:activation of phospholipase C activity, P:activation of protein kinase A activity, P:adenosine receptor signaling pathway, P:adenylate cyclase-activating dopamine receptor signaling pathway, P:adenylate cyclase-activating G-protein coupled receptor signaling pathway, P:adenylate cyclase-inhibiting dopamine receptor signaling pathway, P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, P:cellular response to glucagon stimulus, P:energy reserve metabolic process, P:epidermal growth factor receptor signaling pathway, P:fibroblast growth factor receptor signaling pathway, P:innate immune response, P:intracellular signal transduction, P:locomotory behavior, P:neuromuscular process controlling balance, P:neurotrophin TRK receptor signaling pathway, P:small molecule metabolic process, P:synaptic transmission, P:transmembrane transport, P:water transport, F:nucleotide binding, P:cAMP biosynthetic process, F:phosphorus-oxygen lyase activity, P:cyclic nucleotide biosynthetic process, C:endosome, C:integral to membrane, C:membrane raft, C:sarcolemma, F:calcium- and calmodulin-responsive adenylate cyclase activity, P:nerve growth factor receptor signaling pathway, C:intracellular
UniProtAlternative splicing, ATP-binding, cAMP biosynthesis, Cell projection, Cilium, Complete proteome, Disease mutation, Glycoprotein, Lyase, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Phosphoprotein, Reference proteome, Repeat, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50BloodRRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.372.20E-0220136355

Compile date 09-07-2016© MuScle project