MuScle-logoMuScle - Molecule ID B0376

geneADCY4
nameAdenylate cyclase 4
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADCY4_HUMANQ8NFM4ENSG00000129467196883Hs.443428600292

Functions and classifications

GOC:cytoplasm, C:dendrite, C:integral component of membrane, C:plasma membrane, F:adenylate cyclase activity, F:ATP binding, F:metal ion binding, P:activation of phospholipase C activity, P:activation of protein kinase A activity, P:adenylate cyclase-activating G-protein coupled receptor signaling pathway, P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, P:cellular response to glucagon stimulus, P:energy reserve metabolic process, P:epidermal growth factor receptor signaling pathway, P:fibroblast growth factor receptor signaling pathway, P:innate immune response, P:intracellular signal transduction, P:neurotrophin TRK receptor signaling pathway, P:synaptic transmission, P:transmembrane transport, P:water transport, F:phosphorus-oxygen lyase activity, P:cyclic nucleotide biosynthetic process, C:intracellular, P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway, F:nucleotide binding, P:cAMP biosynthetic process, C:integral to membrane, P:nerve growth factor receptor signaling pathway
UniProtATP-binding, cAMP biosynthesis, Complete proteome, Glycoprotein, Lyase, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Reference proteome, Repeat, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.315.45E-1022252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)0.560.0231780322491253

Compile date 09-07-2016© MuScle project