MuScle-logoMuScle - Molecule ID B0375

geneADCY3
nameAdenylate cyclase type 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADCY3_HUMANO60266ENSG00000138031109Hs.467898600291

Functions and classifications

GOC:cilium, C:cytoplasm, C:integral component of plasma membrane, F:adenylate cyclase activity, F:ATP binding, F:metal ion binding, P:activation of phospholipase C activity, P:activation of protein kinase A activity, P:adenylate cyclase-activating G-protein coupled receptor signaling pathway, P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, P:cellular response to glucagon stimulus, P:energy reserve metabolic process, P:epidermal growth factor receptor signaling pathway, P:fibroblast growth factor receptor signaling pathway, P:innate immune response, P:intracellular signal transduction, P:neurotrophin TRK receptor signaling pathway, P:sensory perception of smell, P:synaptic transmission, P:transmembrane transport, P:water transport, C:integral component of membrane, F:nucleotide binding, F:phosphorus-oxygen lyase activity, P:cyclic nucleotide biosynthetic process, C:integral to plasma membrane, C:membrane raft, C:nucleus, F:calcium- and calmodulin-responsive adenylate cyclase activity, P:female meiosis, P:nerve growth factor receptor signaling pathway, C:intracellular, C:plasma membrane
UniProtATP-binding, Calmodulin-binding, cAMP biosynthesis, Complete proteome, Glycoprotein, Lyase, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Olfaction, Polymorphism, Reference proteome, Repeat, Sensory transduction, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.849.76E-0320136355
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)1.390.003071620921521
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.800.03184221886806
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.904.88E-0322252466

Compile date 09-07-2016© MuScle project