MuScle-logoMuScle - Molecule ID B0374

geneADCY2
nameAdenylate cyclase 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADCY2_HUMANQ08462ENSG00000078295108Hs.481545103071

Functions and classifications

GOC:cytoplasm, C:dendrite, C:integral component of membrane, C:membrane raft, C:plasma membrane, C:protein complex, F:adenylate cyclase activity, F:adenylate cyclase binding, F:ATP binding, F:calcium- and calmodulin-responsive adenylate cyclase activity, F:metal ion binding, F:protein heterodimerization activity, P:activation of phospholipase C activity, P:activation of protein kinase A activity, P:adenylate cyclase-activating G-protein coupled receptor signaling pathway, P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, P:cellular response to glucagon stimulus, P:energy reserve metabolic process, P:epidermal growth factor receptor signaling pathway, P:fibroblast growth factor receptor signaling pathway, P:innate immune response, P:intracellular signal transduction, P:neurotrophin TRK receptor signaling pathway, P:synaptic transmission, P:transmembrane transport, P:water transport, F:nucleotide binding, P:cAMP biosynthetic process, C:intracellular, P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway, F:phosphorus-oxygen lyase activity, P:cyclic nucleotide biosynthetic process, C:integral to membrane, P:nerve growth factor receptor signaling pathway, C:membrane
UniProtATP-binding, cAMP biosynthesis, Complete proteome, Glycoprotein, Lyase, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.220.0231039221216829

Compile date 09-07-2016© MuScle project