MuScle-logoMuScle - Molecule ID B0373

nameAdenylate cyclase, type 1
speciesHomo sapiens

Molecule reference


Functions and classifications

GOC:integral component of membrane, C:nucleus, C:plasma membrane, F:ATP binding, F:calcium- and calmodulin-responsive adenylate cyclase activity, F:calmodulin binding, F:metal ion binding, P:activation of phospholipase C activity, P:activation of protein kinase A activity, P:adenylate cyclase-activating G-protein coupled receptor signaling pathway, P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, P:axonogenesis, P:cellular response to glucagon stimulus, P:circadian rhythm, P:energy reserve metabolic process, P:epidermal growth factor receptor signaling pathway, P:fibroblast growth factor receptor signaling pathway, P:innate immune response, P:intracellular signal transduction, P:long-term memory, P:neurotrophin TRK receptor signaling pathway, P:response to drug, P:response to lithium ion, P:synaptic transmission, P:transmembrane transport, P:water transport, F:nucleotide binding, F:phosphorus-oxygen lyase activity, P:cyclic nucleotide biosynthetic process, C:integral to membrane, P:nerve growth factor receptor signaling pathway, C:intracellular
UniProtATP-binding, Calmodulin-binding, cAMP biosynthesis, Complete proteome, Glycoprotein, Lyase, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_6_month_follow-up) (Multiple sclerosis)2.364.80E-0217467740
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)0.350.026853421216829

Compile date 09-07-2016© MuScle project