MuScle-logoMuScle - Molecule ID B0360

geneAGPS, AAG5
nameAlkyldihydroxyacetonephosphate synthase, peroxisomal precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADAS_HUMANO00116ENSG000000185108540Hs.516543600121, 603051

Functions and classifications

GOC:mitochondrion, C:peroxisomal matrix, C:peroxisomal membrane, F:alkylglycerone-phosphate synthase activity, F:FAD binding, F:UDP-N-acetylmuramate dehydrogenase activity, P:ether lipid biosynthetic process, F:flavin adenine dinucleotide binding, P:lipid biosynthetic process, "C:mitochondrion, F:oxidoreductase activity, acting on CH-OH group of donors, P:lipid biosynthetic process", P:response to chemical stimulus, C:peroxisome, P:response to chemical stimulus"
UniProtAcetylation, Cataract, Complete proteome, Disease mutation, Dwarfism, FAD, Flavoprotein, Lipid biosynthesis, Lipid metabolism, Membrane, Peroxisome, Reference proteome, Rhizomelic chondrodysplasia punctata, Transferase, Transit peptide, Phosphoprotein
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)1.203.31E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)1.261.14E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.120.0337982220136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_24_month_follow-up) (Multiple sclerosis)1.380.012557121886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.377.74E-0321886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.381.83E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.400.008334421886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_3_month_follow-up) (Multiple sclerosis)1.480.0034292321886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.398.65E-0522021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.528.84E-0522021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.705.80E-0722021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.270.038551922252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.350.04482922252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.811.95E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.322.57E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.821.68E-0422252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.802.11E-0323895517

Compile date 09-07-2016© MuScle project