MuScle-logoMuScle - Molecule ID B0355

geneADAM7, GP83
nameDisintegrin and metalloproteinase domain-containing protein 7
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADAM7_HUMANQ9H2U9ENSG000000692068756Hs.116147607310

Functions and classifications

GOC:integral component of membrane, C:plasma membrane, F:metalloendopeptidase activity, F:zinc ion binding, P:proteolysis, C:integral to membrane
UniProtComplete proteome, Disulfide bond, Glycoprotein, Membrane, Polymorphism, Reference proteome, Signal, Transmembrane, Transmembrane helix
PADBDEV: development, cell growth, differentiation, morphogenesis

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)0.100.020905921216829
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.150.046600821886806
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)6.150.001578422491253
Exp24850724Homo sapiens12Blood CIS (Multiple sclerosis)1.820.037034424850724

Compile date 09-07-2016© MuScle project