MuScle-logoMuScle - Molecule ID B0345

nameAlpha-2B adrenergic receptor
speciesHomo sapiens

Molecule reference


Functions and classifications

GOC:integral component of plasma membrane, F:alpha2-adrenergic receptor activity, F:epinephrine binding, P:activation of MAPK activity by adrenergic receptor signaling pathway, P:activation of protein kinase B activity, P:angiogenesis, P:cell-cell signaling, P:epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway, P:female pregnancy, P:MAPK cascade, P:negative regulation of epinephrine secretion, P:negative regulation of norepinephrine secretion, P:platelet activation, P:positive regulation of blood pressure, P:positive regulation of neuron differentiation, P:positive regulation of uterine smooth muscle contraction, P:regulation of vascular smooth muscle contraction, C:integral component of membrane, C:plasma membrane, P:activation of MAPK activity, P:adrenergic receptor signaling pathway, C:integral to plasma membrane, C:integral to membrane
UniProt3D-structure, Cell membrane, Complete proteome, Disulfide bond, G-protein coupled receptor, Lipoprotein, Membrane, Palmitate, Polymorphism, Receptor, Reference proteome, Transducer, Transmembrane, Transmembrane helix
PADBRCP: receptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.702.78E-0422252466

Compile date 09-07-2016© MuScle project