MuScle-logoMuScle - Molecule ID B0342

geneADAM28, ADAM23, MDCL
nameADAM 28 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADA28_HUMANQ9UKQ2ENSG0000004298010863Hs.174030606188

Functions and classifications

GOC:extracellular region, C:integral component of membrane, C:plasma membrane, F:metalloendopeptidase activity, F:metallopeptidase activity, F:zinc ion binding, P:proteolysis, P:spermatogenesis, P:integrin-mediated signaling pathway, C:integral to membrane, F:metal ion binding
UniProtAlternative splicing, Cell membrane, Cleavage on pair of basic residues, Complete proteome, Disulfide bond, EGF-like domain, Glycoprotein, Hydrolase, Membrane, Metal-binding, Metalloprotease, Polymorphism, Protease, Reference proteome, Secreted, Signal, Transmembrane, Transmembrane helix, Zinc, Zymogen, Integrin
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.683.16E-0220136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.374.53E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.572.82E-0221886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.486.00E-0522021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.528.22E-0622021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.792.40E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.833.28E-0222021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.570.018508422252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.977.43E-0522252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)3.146.82E-0622252466

Compile date 09-07-2016© MuScle project