MuScle-logoMuScle - Molecule ID B0341

geneADAM23, MDC3
nameADAM 23 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADA23_HUMANO75077ENSG000001149488745Hs.370287603710

Functions and classifications

GOC:extracellular region, C:integral component of plasma membrane, F:integrin binding, F:metalloendopeptidase activity, F:metallopeptidase activity, F:zinc ion binding, P:cell adhesion, P:central nervous system development, P:proteolysis, P:integrin-mediated signaling pathway, C:integral to plasma membrane, F:metal ion binding
UniProtAlternative splicing, Cell adhesion, Cell membrane, Cleavage on pair of basic residues, Complete proteome, Disulfide bond, EGF-like domain, Glycoprotein, Membrane, Reference proteome, Secreted, Signal, Transmembrane, Transmembrane helix, Integrin, Hydrolase, Metal-binding, Metalloprotease, Protease
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.580.0352175120136355
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.743.67E-0322252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)2.850.021939722491253

Compile date 09-07-2016© MuScle project