MuScle-logoMuScle - Molecule ID B0340

geneADAM22, MDC2
nameADAM 22 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADA22_HUMANQ9P0K1ENSG0000000827753616Hs.256398603709

Functions and classifications

GOC:integral component of membrane, F:integrin binding, F:metalloendopeptidase activity, F:zinc ion binding, P:adult locomotory behavior, P:cell adhesion, P:central nervous system development, P:myelination in peripheral nervous system, P:negative regulation of cell adhesion, P:proteolysis, P:integrin-mediated signaling pathway, C:extracellular region, C:integral to membrane, F:metal ion binding
UniProt3D-structure, Alternative splicing, Cell adhesion, Cleavage on pair of basic residues, Complete proteome, Disulfide bond, EGF-like domain, Glycoprotein, Membrane, Phosphoprotein, Polymorphism, Receptor, Reference proteome, Signal, Transmembrane, Transmembrane helix, Integrin, Secreted, Hydrolase, Metal-binding, Metalloprotease, Protease
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)0.780.0168510320136355
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)0.040.007961221216829
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_12_month_follow-up) (Multiple sclerosis)0.840.0469518321886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.319.45E-0321886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.200.04220421886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.240.029636821886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_3_month_follow-up) (Multiple sclerosis)0.820.0274964721886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.891.44E-0222021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)1.246.23E-0322252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.247.99E-0522252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.224.97E-1222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)3.613.70E-1322252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)0.170.0049498822491253
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)2.740.0461209922491253
Exp24850724Homo sapiens12Blood CIS (Multiple sclerosis)2.190.0123661224850724

Compile date 09-07-2016© MuScle project