MuScle-logoMuScle - Molecule ID B0336

geneADRA1B
nameAlpha-1B adrenergic receptor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADA1B_HUMANP35368ENSG00000170214147Hs.368632104220

Functions and classifications

GOC:integral component of plasma membrane, C:nuclear membrane, F:alpha1-adrenergic receptor activity, F:protein heterodimerization activity, P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway, P:adult heart development, P:behavioral response to cocaine, P:blood vessel remodeling, P:cell growth, P:cell proliferation, P:cell-cell signaling, P:glucose homeostasis, P:intracellular signal transduction, P:locomotory behavior, P:multicellular organismal development, P:negative regulation of glycogen catabolic process, P:organ growth, P:positive regulation of glycogen catabolic process, P:positive regulation of heart rate by epinephrine-norepinephrine, P:positive regulation of MAPK cascade, P:positive regulation of the force of heart contraction by epinephrine-norepinephrine, P:regulation of cardiac muscle contraction, P:regulation of vasoconstriction, P:response to amphetamine, P:response to morphine, P:vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure, P:visual learning, C:integral to plasma membrane, P:intracellular protein kinase cascade
UniProtCell membrane, Complete proteome, Disulfide bond, G-protein coupled receptor, Glycoprotein, Lipoprotein, Membrane, Nucleus, Palmitate, Polymorphism, Receptor, Reference proteome, Transducer, Transmembrane, Transmembrane helix, Phosphoprotein
PADBRCP: receptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10BloodRRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)0.693.94E-0217467740

Compile date 09-07-2016© MuScle project