MuScle-logoMuScle - Molecule ID B0331

geneADAM15, MDC15
nameA disintegrin and metalloproteinase domain 15 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADA15_HUMANQ13444ENSG000001435378751Hs.312098605548

Functions and classifications

GOC:acrosomal vesicle, C:adherens junction, C:cell projection, C:endomembrane system, C:integral component of membrane, F:metalloendopeptidase activity, F:metallopeptidase activity, F:zinc ion binding, P:angiogenesis, P:cardiac epithelial to mesenchymal transition, P:cell-matrix adhesion, P:collagen catabolic process, P:proteolysis, P:tissue regeneration, P:integrin-mediated signaling pathway, C:extracellular region, C:flagellum, C:integral to membrane, F:metal ion binding
UniProtAlternative splicing, Angiogenesis, Cell adhesion, Cell junction, Cell projection, Cleavage on pair of basic residues, Collagen degradation, Complete proteome, Cytoplasmic vesicle, Disulfide bond, EGF-like domain, Glycoprotein, Hydrolase, Membrane, Metal-binding, Metalloprotease, Phosphoprotein, Polymorphism, Protease, Reference proteome, SH3-binding, Signal, Transmembrane, Transmembrane helix, Zinc, Zymogen, Integrin
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.150.0081619521216829
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.061.99E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.353.50E-0222021740

Compile date 09-07-2016© MuScle project