MuScle-logoMuScle - Molecule ID B0319

geneACVR1C, ALK7
nameActivin receptor type-1C
speciesHomo sapiens

Molecule reference


Functions and classifications

GOC:activin receptor complex, F:activin receptor activity, type I, F:ATP binding, F:metal ion binding, F:nodal binding, F:transforming growth factor beta-activated receptor activity, P:apoptotic nuclear changes, P:cell differentiation, P:lipid storage, P:negative regulation of chorionic trophoblast cell proliferation, P:negative regulation of insulin secretion, P:negative regulation of trophoblast cell migration, P:nodal signaling pathway, P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, P:response to dietary excess, P:response to glucose, P:response to insulin, P:response to insulin, P:response to glucose stimulus, P:response to insulin stimulus", P:response to insulin stimulus
UniProtAlternative splicing, Apoptosis, ATP-binding, Complete proteome, Kinase, Magnesium, Manganese, Membrane, Metal-binding, Nucleotide-binding, Polymorphism, Receptor, Reference proteome, Serine/threonine-protein kinase, Signal, Transferase, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.820.017261822252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.621.50E-0322252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.853.03E-0323895517

Compile date 09-07-2016© MuScle project