MuScle-logoMuScle - Molecule ID B0300

geneACTB, PS1TP5BP1
nameActin, cytoplasmic 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACTB_HUMANP60709ENSG0000007562460Hs.520640102630, 243310, 607371

Functions and classifications

GOC:axon, C:cortical cytoskeleton, C:cytoskeleton, C:cytosol, C:extracellular vesicular exosome, C:MLL5-L complex, C:NuA4 histone acetyltransferase complex, C:postsynaptic density, C:ribonucleoprotein complex, F:ATP binding, F:structural constituent of cytoskeleton, P:'de novo' posttranslational protein folding, P:adherens junction organization, P:axon guidance, P:blood coagulation, P:cell junction assembly, P:Fc-gamma receptor signaling pathway involved in phagocytosis, P:innate immune response, C:cytoplasm, C:filamentous actin, C:myofibril, P:axonogenesis, P:sarcomere organization, C:protein complex, P:cellular component movement, P:response to calcium ion
UniProt3D-structure, Acetylation, ATP-binding, Complete proteome, Cytoplasm, Cytoskeleton, Deafness, Direct protein sequencing, Disease mutation, Dystonia, Mental retardation, Methylation, Nucleotide-binding, Oxidation, Polymorphism, Reference proteome, Ubl conjugation
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)2.153.74E-0417467740
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.892.76E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.892.96E-0220136355
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.072.78E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.143.49E-0422021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.143.72E-0422021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.167.66E-0522021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)2.363.21E-0922021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)3.012.64E-0922021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.382.52E-0822252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.773.96E-0322252466

Compile date 09-07-2016© MuScle project