MuScle-logoMuScle - Molecule ID B0292

geneACSL6, ACS2, FACL6
nameLong-chain-fatty-acid--CoA ligase 6
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACSL6_HUMANQ9UKU0ENSG0000016439823305Hs.14945604443

Functions and classifications

GOC:endoplasmic reticulum membrane, C:integral component of membrane, C:membrane, C:mitochondrial outer membrane, C:nucleus, C:peroxisomal membrane, C:plasma membrane, F:ATP binding, F:long-chain fatty acid-CoA ligase activity, F:protein homodimerization activity, P:cellular response to insulin stimulus, P:fatty acid transport, P:long-chain fatty-acyl-CoA biosynthetic process, P:neuroblast proliferation, P:neuron development, P:phospholipid biosynthetic process, P:positive regulation of neuron projection development, P:positive regulation of plasma membrane long-chain fatty acid transport, P:positive regulation of triglyceride biosynthetic process, P:response to gravity, P:response to hypoxia, P:response to nutrient, P:response to steroid hormone, P:triglyceride biosynthetic process, C:mitochondrion, P:triglyceride metabolic process, F:catalytic activity, F:ligase activity, C:integral to membrane, P:long-chain fatty acid metabolic process
UniProtAlternative splicing, ATP-binding, Chromosomal rearrangement, Complete proteome, Endoplasmic reticulum, Fatty acid metabolism, Ligase, Lipid metabolism, Magnesium, Membrane, Microsome, Mitochondrion, Mitochondrion outer membrane, Nucleotide-binding, Peroxisome, Reference proteome, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.331.14E-0922252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.495.06E-0822252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)2.070.0343818522491253

Compile date 09-07-2016© MuScle project