MuScle-logoMuScle - Molecule ID B0291

geneACSL5, ACS5, FACL5
nameLong-chain-fatty-acid--CoA ligase 5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACSL5_HUMANQ9ULC5ENSG0000019714251703Hs.11638605677

Functions and classifications

GOC:endoplasmic reticulum, C:endoplasmic reticulum membrane, C:integral component of membrane, C:mitochondrial inner membrane, C:mitochondrial outer membrane, C:mitochondrion, F:ATP binding, F:long-chain fatty acid-CoA ligase activity, P:long-chain fatty acid metabolic process, P:long-chain fatty-acyl-CoA biosynthetic process, P:regulation of extrinsic apoptotic signaling pathway, P:triglyceride biosynthetic process, F:ligase activity, C:integral to membrane, P:cellular response to insulin stimulus, P:fatty acid transport, P:positive regulation of plasma membrane long-chain fatty acid transport, P:positive regulation of triglyceride biosynthetic process, P:regulation of apoptotic process, P:response to cholesterol, P:response to glucose stimulus, P:response to nutrient, P:response to sucrose stimulus
UniProtAcetylation, Alternative splicing, ATP-binding, Complete proteome, Endoplasmic reticulum, Fatty acid metabolism, Ligase, Lipid metabolism, Magnesium, Membrane, Mitochondrion, Mitochondrion outer membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Signal-anchor, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.361.39E-0221886806
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.170.041098322252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.743.40E-0322252466

Compile date 09-07-2016© MuScle project