MuScle-logoMuScle - Molecule ID B0284

geneACSS1, ACAS2L
nameAcetyl-coenzyme A synthetase 2-like, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACS2L_HUMANQ9NUB1ENSG0000015493084532Hs.529353614355

Functions and classifications

GOC:mitochondrial matrix, F:acetate-CoA ligase activity, F:AMP binding, F:ATP binding, P:acetate biosynthetic process, P:acetyl-CoA biosynthetic process, P:acetyl-CoA biosynthetic process from acetate, P:ethanol oxidation, P:propionate biosynthetic process, P:xenobiotic metabolic process, F:catalytic activity, P:metabolic process, C:mitochondrion
UniProt3D-structure, Acetylation, Alternative splicing, ATP-binding, Complete proteome, Direct protein sequencing, Ligase, Mitochondrion, Nucleotide-binding, Polymorphism, Reference proteome, Transit peptide
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.703.06E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)1.561.14E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.510.0167176420136355
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.210.0164421721216829
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.624.97E-0321886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.739.32E-0622021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.871.29E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.517.50E-0322252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)3.461.05E-0622252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)4.321.88E-1022252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.201.70E-0523895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.221.05E-0323895517

Compile date 09-07-2016© MuScle project