MuScle-logoMuScle - Molecule ID B0273

geneACOX1, ACOX
nameAcyl-coenzyme A oxidase 1, peroxisomal
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACOX1_HUMANQ15067ENSG0000016153351Hs.464137264470, 609751

Functions and classifications

GOC:mitochondrion, C:peroxisomal matrix, C:peroxisomal membrane, F:acyl-CoA dehydrogenase activity, F:acyl-CoA oxidase activity, F:FAD binding, F:fatty acid binding, F:flavin adenine dinucleotide binding, F:palmitoyl-CoA oxidase activity, P:alpha-linolenic acid metabolic process, P:fatty acid beta-oxidation using acyl-CoA oxidase, P:fatty acid oxidation, P:generation of precursor metabolites and energy, P:lipid homeostasis, P:peroxisome fission, P:positive regulation of cholesterol homeostasis, P:prostaglandin metabolic process, P:spermatogenesis, P:very long-chain fatty acid metabolic process, C:peroxisome, P:fatty acid beta-oxidation
UniProtAcetylation, Alternative splicing, Complete proteome, Disease mutation, FAD, Fatty acid metabolism, Flavoprotein, Lipid metabolism, Oxidoreductase, Peroxisome, Phosphoprotein, Polymorphism, Reference proteome
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.824.68E-0420136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)1.300.0017056120136355
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.200.0231097721216829
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.392.07E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_3_month_follow-up) (Multiple sclerosis)0.750.0490347221886806
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.210.011721122252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.561.99E-0622252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.161.03E-0323895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.198.96E-0423895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.259.55E-0623895517
Exp24850724Homo sapiens12Blood CIS (Multiple sclerosis)2.410.0095589124850724

Compile date 09-07-2016© MuScle project