MuScle-logoMuScle - Molecule ID B0247

geneACKR3, CXCR7, CMKOR1
nameAtypical chemokine receptor 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACKR3_HUMANP25106ENSG0000014447657007Hs.471751610376

Functions and classifications

GOC:cell surface, C:coated pit, C:early endosome, C:endosome, C:integral component of membrane, C:perinuclear region of cytoplasm, C:plasma membrane, C:recycling endosome, F:C-X-C chemokine binding, F:C-X-C chemokine receptor activity, F:coreceptor activity, F:scavenger receptor activity, P:angiogenesis, P:cell adhesion, P:chemotaxis, P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage, P:positive regulation of ERK1 and ERK2 cascade, P:receptor internalization, P:vasculogenesis, P:viral process, C:integral to membrane, P:multicellular organismal development, P:negative regulation of apoptotic process, P:virus-host interaction
UniProtCell adhesion, Cell membrane, Complete proteome, Cytoplasm, Developmental protein, Disulfide bond, Endosome, G-protein coupled receptor, Glycoprotein, Host-virus interaction, Membrane, Phosphoprotein, Polymorphism, Receptor, Reference proteome, Transducer, Transmembrane, Transmembrane helix, Ubl conjugation
PADBRCP: receptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.850.0447314520136355
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.973.53E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.209.74E-0422252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.104.85E-0423895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.263.70E-0523895517
Exp24850724Homo sapiens12Blood CIS (Multiple sclerosis)1.860.0074022824850724

Compile date 09-07-2016© MuScle project