MuScle-logoMuScle - Molecule ID B0246

geneACKR2, CCBP2, CCR10
nameAtypical chemokine receptor 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACKR2_HUMANO00590ENSG000001446481238Hs.146346602648

Functions and classifications

GOC:actin filament, C:early endosome, C:integral component of plasma membrane, C:recycling endosome, F:C-C chemokine receptor activity, F:C-X-C chemokine receptor activity, F:chemokine receptor activity, F:scavenger receptor activity, P:chemotaxis, P:immune response, P:inflammatory response, P:multicellular organismal development, P:neutrophil activation, C:integral component of membrane, P:chemokine-mediated signaling pathway, C:integral to plasma membrane, C:integral to membrane
UniProtCell membrane, Complete proteome, Disulfide bond, Endosome, G-protein coupled receptor, Glycoprotein, Inflammatory response, Membrane, Phosphoprotein, Polymorphism, Receptor, Reference proteome, Transducer, Transmembrane, Transmembrane helix
PADBRCP: receptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.792.64E-0222252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.953.94E-0223895517

Compile date 09-07-2016© MuScle project