MuScle-logoMuScle - Molecule ID B0223

geneACER1, ASAH3
nameAlkaline ceramidase 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACER1_HUMANQ8TDN7ENSG00000167769125981Hs.352609613491

Functions and classifications

GOC:endoplasmic reticulum membrane, C:integral component of membrane, F:dihydroceramidase activity, P:cellular response to calcium ion, P:ceramide catabolic process, P:keratinocyte differentiation, P:regulation of lipid metabolic process, P:response to alkalinity, P:sphingosine biosynthetic process, C:integral to membrane, P:phospholipid metabolic process
UniProtComplete proteome, Endoplasmic reticulum, Hydrolase, Lipid metabolism, Membrane, Reference proteome, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.883.20E-0222252466

Compile date 09-07-2016© MuScle project