MuScle-logoMuScle - Molecule ID B0222

geneACE2, UNQ868/PRO1885, UNQ868
nameAngiotensin-converting enzyme 2 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACE2_HUMANQ9BYF1ENSG0000013023459272Hs.178098300335

Functions and classifications

GOC:cell surface, C:extracellular space, C:integral component of membrane, C:membrane raft, C:plasma membrane, F:carboxypeptidase activity, F:endopeptidase activity, F:peptide hormone binding, F:virus receptor activity, F:zinc ion binding, P:angiotensin catabolic process in blood, P:angiotensin maturation, P:angiotensin-mediated drinking behavior, P:cellular protein metabolic process, P:positive regulation of reactive oxygen species metabolic process, P:proteolysis, P:receptor biosynthetic process, P:receptor-mediated virion attachment to host cell, P:regulation of cell proliferation, P:regulation of cytokine production, P:regulation of inflammatory response, P:regulation of vasoconstriction, P:regulation of vasodilation, P:viral entry into host cell, C:membrane, F:metallopeptidase activity, F:peptidyl-dipeptidase activity, "C:cell surface, C:integral to membrane, F:metal ion binding, F:viral receptor activity, P:virion attachment, binding of host cell surface receptor"
UniProt3D-structure, Alternative splicing, Carboxypeptidase, Cell membrane, Chloride, Complete proteome, Direct protein sequencing, Disulfide bond, Glycoprotein, Host-virus interaction, Hydrolase, Membrane, Metal-binding, Metalloprotease, Polymorphism, Protease, Reference proteome, Secreted, Signal, Transmembrane, Transmembrane helix, Zinc
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50BloodRRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.740.0412383520136355

Compile date 09-07-2016© MuScle project