MuScle-logoMuScle - Molecule ID B0221

geneACE, DCP, DCP1
nameAngiotensin-converting enzyme, somatic isoform precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACE_HUMANP12821ENSG00000159640|ENSG000002648131636Hs.298469106180, 267430, 601367, 612624, 614519

Functions and classifications

GOC:endosome, C:external side of plasma membrane, C:extracellular space, C:integral component of membrane, C:plasma membrane, F:actin binding, F:carboxypeptidase activity, F:chloride ion binding, F:drug binding, F:endopeptidase activity, F:metallopeptidase activity, F:peptidyl-dipeptidase activity, F:zinc ion binding, P:angiotensin catabolic process in blood, P:angiotensin maturation, P:arachidonic acid secretion, P:blood vessel remodeling, P:cellular protein metabolic process, P:hematopoietic stem cell differentiation, P:hormone catabolic process, P:kidney development, P:mononuclear cell proliferation, P:peptide catabolic process, P:proteolysis, P:regulation of renal output by angiotensin, P:regulation of smooth muscle cell migration, P:regulation of vasoconstriction, P:regulation of vasodilation, C:membrane, C:integral to membrane, F:metal ion binding
UniProt3D-structure, Alternative splicing, Carboxypeptidase, Cell membrane, Complete proteome, Direct protein sequencing, Disulfide bond, Glycoprotein, Hydrolase, Membrane, Metal-binding, Metalloprotease, Phosphoprotein, Polymorphism, Protease, Reference proteome, Repeat, Secreted, Signal, Transmembrane, Transmembrane helix, Zinc
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)3.238.74E-0722252466

Compile date 09-07-2016© MuScle project