MuScle-logoMuScle - Molecule ID B0217

geneACD, PIP1, PTOP
nameAdrenocortical dysplasia protein homolog
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACD_HUMANQ96AP0ENSG0000010297765057Hs.78019609377

Functions and classifications

GOC:nuclear telomere cap complex, C:nucleoplasm, C:telomerase holoenzyme complex, F:telomeric DNA binding, P:embryonic limb morphogenesis, P:intracellular protein transport, P:negative regulation of telomere maintenance via telomerase, P:positive regulation of single-stranded telomeric DNA binding, P:positive regulation of telomerase activity, P:protection from non-homologous end joining at telomere, P:protein localization to chromosome, telomeric region, P:segmentation, P:skeletal system development, P:telomere assembly, P:telomere maintenance via telomerase, P:urogenital system development, "C:chromosome, telomeric region, P:telomere maintenance via telomerase", F:DNA binding
UniProt3D-structure, Alternative splicing, Chromosome, Complete proteome, DNA-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Telomere
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_6_month_follow-up) (Multiple sclerosis)1.583.68E-0217467740
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.810.0262520420136355
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.138.58E-0322021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.370.002955122252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.346.09E-0322252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.112.15E-0223895517

Compile date 09-07-2016© MuScle project